01.06.2015 von 17:15 bis 18:45

Institut für Materialwissenschaft, Kaiser Str. 2, Geb.C , Raum "Aquarium"

Titel: Optical control and biomedical applications of HOT nanoparticles

Precise optical control over individual metallic nanoparticles has huge potential for nano-architectural purposes. The talk will commence by explaining how a focused laser beam can control not only the position, but also the orientation of a single nanoparticle [1]. While optically manipulating metallic nanostructures, it is worth noting that absorption and heating associated with resonant irradiation of metallic nanoparticles can be extreme [2]. Moreover, the heating of a nanoparticle cannot be theoretically predicted as the precise focal intensity distribution on the nanoscale is unknown and typically highly aberrated [3]. Utilizing a novel membrane-based assay we directly quantify the heating of an individual irradiated gold nanoparticle and show how this depends on laser power and particle size, shape, orientation and composition [4,5]. Also, our novel results show how the photo-thermal effect of metallic nanoparticles can be used to create localized heat gradients inside living cells, which is highly useful for targeted drug delivery and for photothermal treatment of cancers.

[1] Selhuber-Unkel et al., Quantitative optical trapping of single gold nanorods. Nano Letters, vol. 8, p. 2998-3003 (2008).

[2] Bendix et al., Direct measurements of heating by electromagnetically trapped gold nanoparticles on supported lipid bilayers, ACS Nano, vol. 4 p.2256-2262 (2010).

[3] Kyrsting et al., Mapping 3D focal intensity exposes the stable trapping positions of single nanoparticles. Nano Letters vol.13 p.31-35 (2013).

[4] Ma et al., Large-Scale Orientation Dependent Heating from a Single Irradiated Gold Nanorod. Nano Letters vol.12 p.3954-3960 (2012).

[5] Ma et al., Heat generation by irradiated complex composite nanostructures. Nano Letters, vol. 14 p.612-619 (2014).

Prof. Christine Selhuber-Unkel

Diesen Termin meinem iCal-Kalender hinzufügen

zurück