Kolloquium Prof. Dr. Andreas Taubert, Universität Potsdam / 11.04.2016

11.04.2016 von 17:15 bis 18:45

Institut für Materialwissenschaft, Raum: Geb. D, Aquarium, Kaiserstraße 2, 24143 Kiel

Titel: Biomimetic calcium phosphate mineralization - effects of surfaces and interfaces


Calcium phosphate is one of the most important biominerals. It comes in a variety of phases, e.g. hydroxyapatite, brushite, etc., and is a key component in bones, teeth, and tendons.1,2 Biomimetic calcium phosphate mineralization, that is, the synthesis of calcium phosphate/organic composites using a synthetic template or additive, provides access to a large variety of calcium phosphate composites that could for instance be useful for bone repair. However, the details of calcium phosphate nucleation, growth, and phase selection are not fully understood yet. To rationally design tailored materials for specific applications such as healthcare, this would however be essential.Among others, interfaces are a key factor affecting the formation, structure, composition, and properties of both the calcium phosphate deposits and the resulting hybrid materials. In spite of this, there are only relatively few studies on the role of surfaces and interfaces on calcium phosphate growth.The presentation will present data on calcium phosphate formation on model surfaces, both at the solid-liquid3 and the liquid-air interface,4-7 and discuss the effects of these interfaces on crystal formation. A special focus is put on the effects of polycations, such as poly(2-dimethylethylamino methacrylate) (PDMAEMA), because polycations have been less extensively studied than polyanions and there is hence a lack of information on their role in calcium phosphate mineralization. This also applies to the effects of oligomeric compounds as mineralization templates.8 Our studies show that not only the type of surface (anionic vs. cationic) but also the charge of each polymer surface (charged vs. uncharged) strongly affects the outcome of the mineralization process. A preliminary hypothesis of how polycations may regulate calcium phosphate is also proposed9 and – time permitting – I will also present some recent data on how ionic liquids can be used to generate interesting composite materials.10



(1)       Calcium Phosphates in Biological and Industrial Systems; Kluwer Academic Publishers: Norwell-Dordrecht, 1998.

(2)       Handbook of Biomineralization; Wiley-VCH: Weinheim, 2007.

(3)       Löbbicke, R.; Chanana, M.; Schlaad, H.; Pilz-Allen, C.; Günter, C.; Möhwald, H.; Taubert, A. Biomacromolecules 2011, 12, 3753.

(4)       Casse, O.; Colombani, O.; Kita-Tokarczyk, K.; Müller, A. H. E.; Meier, W.; Taubert, A. Faraday Discuss. 2008, 139, 179.

(5)       Junginger, M.; Bleek, K.; Kita-Tokarczyk, K.; Reiche, J.; Shkilnyy, A.; Schacher, F.; Müller, A. H. E.; Taubert Nanoscale 2010, 2, 2440.

(6)       Junginger, M.; Kita-Tokarczyk, K.; Schuster, T.; Reiche, J.; Schacher, F. A.; Müller, A. H. E.; Cölfen, H.; Taubert, A. Macromol. Biosci. 2010, 10, 1084.

 (7)       Junginger, M.; Kübel, C.; Schacher, F. H.; Müller, A. H. E.; Taubert, A. RSC Adv. 2013, 3, 11301.

 (8)       Hentrich, D.; Junginger, M.; Bruns, M.; Börner, H. G.; Brandt, J.; Brezesinski, G.; Taubert, A. Cryst. Eng. Comm. 2015, DOI: 10.1039/C4CE02274B

 (9)       Shkilnyy, A.; Schöne, S.; Rumplasch, C.; Uhlmann, A.; Hedderich, A.; Taubert, A. Colloid Polym. Sci. 2011, 289, 881.

(10)     Salama, A.; Neumann, M.; Günter, C.; Taubert, A. Beilstein. J. Nanotechnol. 2014, 5, 1553.


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