Kolloquiumsvortrag (MaWi), Prof. Friedrich Frischknecht, Universität Heidelberg / am 11.12.2017

11.12.2017 von 17:15 bis 18:00

Institute Ostufer, Geb. D, "Aquarium", Kaiserstr. 2, 24143 Kiel

Titel: Malaria transmission: new insights from in vivo imaging and materials science

Abstract: Malaria parasites are transmitted by mosquitoes and multiply to large numbers in red blood cells to cause disease. When taken up by mosquitoes the parasite develop in large cysts in their guts from where they emerge to colonize the salivary glands of the insect. From there the parasites are injected into the skin where they have to migrate to find a blood vessel. After entering the blood vessel the parasites first enter liver cells where they multiply without causing disease symptoms. In this seminar I will illuminate some of this curious biology using a set of different microscopy techniques, molecular genetics and biophysical approaches. We will see how parasites form within the cysts, how they leave the cysts, move within salivary glands and in the skin. Using laser tweezers we have measured the force they can produce and using micro-pillar arrays we have asked whether they adapted their shape in order to find the small blood capillaries into which they enter. For more info see: www.sporozoite.org

Prof. Selhuber

Diesen Termin meinem iCal-Kalender hinzufügen